Tag: <span>viral infections</span>

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Recurrent wheezing in children linked to ‘silent’ viral infections
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Recurrent wheezing in children linked to ‘silent’ viral infections

News Release 8-Aug-2024 Peer-Reviewed PublicationUniversity of Virginia Health System image: “We hope this discovery will stimulate further work in the treatment of recurrent wheeze and viral infections in children,” said researcher W. Gerald Teague, MD, a pediatric pulmonologist at UVA Health Children’s and the University of Virginia School of Medicine. “The field has to get...

The impact of viral infections on the human endocrine system
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The impact of viral infections on the human endocrine system

By Neha Mathur Feb 3 2023 Reviewed by Danielle Ellis, B.Sc. In a recent study published in Microorganisms, researchers briefly outlined how viral infections trigger endocrinopathies in humans. Study: Viruses and Endocrine Diseases. Image Credit: mediatext/Shutterstock Background Viruses can transiently or permanently damage endocrine organs by directly attacking endocrine cells or via indirect mechanisms. It activates the...

Study suggests a way to re-energize tired T cells when treating cancer, viral infections
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Study suggests a way to re-energize tired T cells when treating cancer, viral infections

by Ohio State University Medical Center Scanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAID A new study by researchers at The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James) suggests a...

An investigational T-cell therapy shows promise against six viral infections common after stem cell transplants
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An investigational T-cell therapy shows promise against six viral infections common after stem cell transplants

by American Association for Cancer Research Credit: Unsplash/CC0 Public Domain Posoleucel, an investigational allogeneic off-the-shelf T-cell therapy that simultaneously targets six different viruses, demonstrated promising antiviral efficacy and safety in a phase II study of patients who had undergone stem cell transplantation to treat their cancer or other blood diseases, according to a publication in...

Researchers discover a new type of RNA that inhibits a broad range of viral infections
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Researchers discover a new type of RNA that inhibits a broad range of viral infections

by Lindsay Brownell, Harvard University Graphical abstract. Credit: Molecular Therapy – Nucleic Acids (2022). DOI: 10.1016/j.omtn.2022.08.031 RNA is often described as the single-stranded cousin of DNA, the double-stranded molecule that makes up the genomes of all living organisms. Many types of non-living viruses, however, carry their genetic information in a double-stranded form of RNA (dsRNA). When the...

How T cells safeguard the frontline from viral infections and certain cancers
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How T cells safeguard the frontline from viral infections and certain cancers

by Peter Doherty Institute for Infection and Immunity  Credit: Nature Immunology (2022). DOI: 10.1038/s41590-022-01273-4. https://www.nature.com/articles/s41590-022-01273-4 Researchers at the Peter Doherty Institute for Infection and Immunity (Doherty Institute) have identified how to increase the ability of tissue-resident memory T (TRM) cells to help fight viral infections and certain cancers. This discovery adds to the growing knowledge around the huge...

Type-I interferon stops immune system from ‘going rogue’ during viral infections
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Type-I interferon stops immune system from ‘going rogue’ during viral infections

by McMaster University Credit: CC0 Public Domain McMaster University researchers have found not only how some viral infections cause severe tissue damage, but also how to reduce that damage. They have discovered how Type I interferon (IFN) stops the immune system from “going rogue” and attacking the body’s own tissues when fighting viral infections, including COVID-19....

Stowaway B cells in the lungs bear the blueprint to fight the flu, and possibly other viral infections
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Stowaway B cells in the lungs bear the blueprint to fight the flu, and possibly other viral infections

by Delthia Ricks, Medical Xpress Characterisation of memory B cell responses in mice after influenza infection. (A) Representative gating for memory B cells. After doublet, dead and CD3+, F4/80+ and streptavidin-specific cells were removed, CD45+ B220+ IgD- lymphocytes were gated before assessing binding to HA- or NP-probes within memory populations (GL7-CD38hi). (B) Proportion of blood-circulating (IV+; red) and tissue-resident...

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