by Tokyo Medical and Dental University PD-1+CD8+ T cells were activated rather than exhausted. PD-1+CD8+ T cells infiltrated muscle tissues. Affected muscles reacted to IFNγ, which could be produced from effector T cells, as a danger signal and then expressed PD-L1. Muscles countered PD-1+CD8+ T cell attacks through the enhancement of PD-L1 expression. Credit: Department of...
NORTHWESTERN UNIVERSITY IMAGE: AN MR IMAGE OF A PATIENT IN THEIR EARLY 20S SHOWS NERVE INJURY OF THE LEFT BRACHIAL PLEXUS IN THE NECK. THE PATIENT EXPERIENCED LEFT ARM WEAKNESS AND PAIN AFTER RECOVERING FROM COVID-19 RESPIROTORY ILLNESS, WHICH PROMTED THEM TO SEE THEIR PRIMARY CARE PHYSICIAN. CREDIT: NORTHWESTERN UNIVERSITY CHICAGO — After recovering from...
Journal of the American Geriatrics Society Research Summary AMERICAN GERIATRICS SOCIETY Cardiovascular disease (also called heart disease) is one of the most common medical conditions older adults face. In nursing homes, almost half of all older adult residents have been diagnosed with problems affecting the heart and/or blood vessels. In spite of this, we know...
by University of California, San Francisco A UC San Francisco-led research team has detected the immunological remnants of a common seasonal virus in spinal fluid from dozens of patients diagnosed with acute flaccid myelitis (AFM)—a polio-like illness that causes permanent, sometimes life-threatening paralysis in young children. The findings provide the clearest evidence to date that...
By Jennifer Huizen Reviewed by Daniel Bubnis, MS, NASM-CPT, NASE Level II-CSS Claudication is muscular pain, cramping, or fatigue that typically occurs during exercise and goes away with rest. Claudication is primarily a symptom of conditions that reduce blood flow in the legs, especially peripheral artery disease (PAD). The term claudication comes from the Latin...
by University of California, San Francisco Two new studies by an international team of researchers report progress in using stem cells to develop new therapies for Pelizaeus-Merzbacher disease (PMD), a rare genetic condition affecting boys that can be fatal before 10 years of age. Often diagnosed at birth with symptoms of weakness and breathing difficulties, the progressive neurological problems in PMD are caused...
