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Engineered White Blood Cells Eliminate Cancer
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Engineered White Blood Cells Eliminate Cancer

Posted on June 12, 2023 Author Melissa Pappas “Macrophages killing cancer cell” photographed by Susan Arnold. By silencing the molecular pathway that prevents macrophages from attacking our own cells, Penn Engineers have manipulated these white blood cells to eliminate solid tumors. Cancer remains one of the leading causes of death in the U.S. at over 600,000 deaths...

Turning white blood cells into medicinal microrobots with light
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Turning white blood cells into medicinal microrobots with light

AMERICAN CHEMICAL SOCIETY IMAGE: A LASER PRECISELY GUIDED A “NEUTROBOT” TOWARD A NANOPARTICLE (LEFT IMAGE), WHICH WAS PICKED UP AND TRANSPORTED AWAY (RIGHT IMAGE). CREDIT: ADAPTED FROM ACS CENTRAL SCIENCE 2022, DOI: 10.1021/ACSCENTSCI.2C00468 Medicinal microrobots could help physicians better treat and prevent diseases. But most of these devices are made with synthetic materials that trigger...

Determining Disease Through White Blood Cells
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Determining Disease Through White Blood Cells

By Dr. Liji Thomas, MD Reviewed by Emily Henderson, B.Sc. White cells are the immune cells of the body. Also called leukocytes, they are useful in fighting infections and belong to five types. About 100 million white cells are produced by the body each day. These include granulocytes, comprising neutrophils, basophils, and eosinophils, and the...

White blood cells that can help destroy malignant tumors
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White blood cells that can help destroy malignant tumors

by  Tel-Aviv University Proliferation metastatic tumor cells in animals with no eosinophils. Credit: Tel Aviv University A new study at Tel Aviv University found that eosinophils—a type of white blood cells—are recruited to the battle against cancer metastases in the lungs. According to the researchers, these white blood cells produce destructive proteins of their own, while at...

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Squishy white blood cells quickly become highly stiff and viscous in response to a threat

CELL PRESS CREDIT: JULIEN HUSSON, LADHYX, CNRS, ÉCOLE POLYTECHNIQUE, INSTITUT POLYTEC Like a well-trained soldier, a white blood cell uses specialized abilities to identify and ultimately destroy dangerous intruders, including creating a protrusion to effectively reach out, lock-on, probe, and possibly attack its prey. Researchers reporting March 16 in Biophysical Journal show in detail that these cells take seconds...

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What to know about white blood cells

White blood cells circulate around the blood and help the immune system fight off infections. Stem cells in the bone marrow are responsible for producing white blood cells. The bone marrow then stores an estimated 80–90% of white blood cells. When an infection or inflammatory condition occurs, the body releases white blood cells to help...

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Adaptive human immunity depends on the factor responsible for the formation of white blood cells

Granulocyte colony-stimulating factor (G-CSF) has a significant regulatory effect not only on innate, but also on adaptive immunity. IMMANUEL KANT BALTIC FEDERAL UNIVERSITY Granulocyte colony-stimulating factor (G-CSF), which causes division and differentiation of bone marrow cells depending on the body’s need for leukocytes, has a significant regulatory effect not only on innate, but also on...

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FDA approves TB pill that cures more hard-to treat patients

by Linda A. Johnson U.S. regulators Wednesday approved a new tuberculosis medicine that shortens and improves treatment for the hardest-to-treat cases, a worsening problem in many poor countries. It’s the first TB drug from a nonprofit group. The TB Alliance, formed to come up with better treatments, developed pretomanid with help from charities and government...

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Decades-old misconception on white blood cell trafficking to spleen corrected

by  University of Turku Contrary to prior belief, white blood cells enter the spleen primarily via vessels in the red pulp. The research results contradict ideas regarding how the spleen produces antibodies vital for the human body. The spleen is our largest lymphoid organ. Its function is to eliminate outdated red blood cells and to produce antibodies against pathogens. Outdated red blood cells...

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