by Elana Gotkine

For children with obstructive sleep apnea (OSA) with nocturnal enuresis (NE), the remission rate of NE is more than half for those undergoing adenoidectomy and/or tonsillectomy, according to a review published online Jan. 25 in the European Archives of Oto-Rhino-Laryngology.

Zhe Wang, from the General Hospital of Northern Theater Command in Shenyang, China, and colleagues conducted a systematic review to examine the efficacy of tonsillectomy and/or adenoidectomy for the treatment of NE in children with OSA.

The researchers found that for children with NE who underwent adenoidectomy and/or tonsillectomy, the combined overall remission (OR), complete remission (CR), and partial remission rates were 67, 57, and 4%, respectively. The pooled OR and CR for primary NE were 67 and 59%, respectively, in children with OSA. For children treated with adenotonsillectomy, the pooled OR was 72%, while the CR was 65%.

For children older than 5 years with OSA, the pooled OR and CR were 67 and 58%, respectively. For postoperative follow-up of no more than three months, the pooled OR and CR were 64 and 52%, respectively. Based on randomized controlled trials, the pooled OR and CR of NE were both 37.3%.

“We should be relatively cautious in interpreting these results and the actual remission rate may be lower than we expected,” the authors write.

More information: Zhe Wang et al, The role of adenoidectomy and/or tonsillectomy in the treatment of nocturnal enuresis in OSA children: a single-arm meta-analysis, European Archives of Oto-Rhino-Laryngology (2025). DOI: 10.1007/s00405-025-09221-2

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