by Brigham and Women’s Hospital Credit: Pixabay/CC0 Public Domain Over 37 million Americans have diabetes, and 90 to 95% of that population are diagnosed with type 2 diabetes. Lifestyle interventions, such as a healthy diet and a regular physical activity program, are methods to manage diabetes. A new study from a collaboration of investigators at Brigham...
by Swansea University Graphical abstract. Credit: Cell Metabolism (2023). DOI: 10.1016/j.cmet.2023.05.001 Swansea University researchers have found that a drug commonly used to treat type 2 diabetes can potentially be used in the treatment of autoimmune disorders. Academics at the University’s Faculty of Medicine, Health and Life Science have found that the drug, canagliflozin (also known as Invokana), could...
by La Jolla Institute for Immunology Credit: Pixabay/CC0 Public Domain A population of unconventional white blood cells has recently captured the attention of immunologists and clinicians alike. Unlike conventional T cells, which circulate throughout the body in our blood, mucosal-associated invariant T (MAIT) cells are largely found in tissues where they provide immune protection against a...
by The Korea Advanced Institute of Science and Technology (KAIST) Genetic composition of rc-L1s is inherited from the parents. The methylation landscape of rc-L1 promoters is predominantly determined by global DNA demethylation, followed by remethylation processes in the developmental stages. Then, when an rc-L1 is promoter demethylated in a specific cell lineage, the source expresses L1...
by University of California, Irvine The 90+ Study, one of the largest studies of its kind in the world, used cognitive assessment test scores from some of the more than 2,000 participants enrolled. The project has produced several significant findings regarding cognitive function, health and lifestyle habits in the oldest-old population information obtained during life. Credit:...
by Atrium Health Wake Forest Baptist Credit: JCI Insight (2023). DOI: 10.1172/jci.insight.162454 It’s well-known that people with type 2 diabetes are at an increased risk of developing Alzheimer’s disease, but the reason why isn’t fully understood and is an area of current research. Now, scientists at Wake Forest University School of Medicine have uncovered a novel mechanism...
by Hong Kong Polytechnic University 3D molecular models of ABarginase, albumin and FcRn receptor on a cell surface. Credit: Hong Kong Polytechnic University Researchers from The Hong Kong Polytechnic University (PolyU) and The Chinese University of Hong Kong (CUHK) have jointly made a groundbreaking drug discovery in treating multiple metabolic diseases related to obesity and insulin...
by Caroline Sheedy, Carnegie Mellon University Credit: Pixabay/CC0 Public Domain In a paper published in Neuron, Aryn Gittis and colleagues present new information about a neural pathway in the basal ganglia, a part of the brain important for skill learning, habit formation and motor control. The paper contradicts the model that has guided researchers’ understanding of motor...
Posted 5 days ago Using X-rays to see inside the human body has revolutionized non-invasive medical diagnostics. However, the dose of X-rays required for imaging is far higher than background levels, due to the poor performance of the detector materials currently available. This can cause harm to patients and in some cases even cancer. Photovoltaic solar panels –...
Posted Today Scientific demonstration with machine learning reveals ‘extreme’ genes – DNA sequences with custom-tailored activities. Artificial intelligence has exploded across our news feeds, with Chat GPT and related AI technologies becoming the focus of broad public scrutiny. Beyond popular chatbots, biologists are finding ways to leverage AI to probe the core functions of our genes....
