Novo Nordisk, a Danish pharmaceutical company, announced yesterday that a late-stage trial demonstrated the efficacy of a high-dose oral version of its drug semaglutide in assisting overweight or obese adults in losing 15% of their body weight. This outcome aligns with recent findings from other experimental obesity pills. Novo Nordisk intends to pursue regulatory approval for the high-dose pill...
Month: <span>July 2023</span>
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New study reveals a potential big leap for gene therapy
AARHUS UNIVERSITY IMAGE: A NEW STUDY LED BY PROFESSOR YONGLUN LUO FROM THE DEPARTMENT OG BIOMEDICINE AT AARHUS UNIVERSITY SHOWS THAT ARTIFICIAL INTELLIGENCE (AI) MAY HOLD THE KEY TO A SHARPER AND MORE PRECISE DNA SCISSOR. THIS DISCOVERY MAY BE A BREAK THROUGH FOR MORE EFFICIENT GENE THERAPY. CREDIT: LINE RØNN, HEALTH AARHUS UNIVERSITY Artificial...
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Lonely people process the world differently, study finds
Reviewed by Lily Ramsey, LLM Jun 28 2023 The Russian writer and philosopher Leo Tolstoy may have been onto something when he wrote the opening line of Anna Karenina: “Happy families are all alike; every unhappy family is unhappy in its own way.” A recent study published in Psychological Science and led by a scholar now at the...
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Benzodiazepine use associated with brain injury, job loss and suicide
by CU Anschutz Medical Campus Credit: CC0 Public Domain Benzodiazepine use and discontinuation is associated with nervous system injury and negative life effects that continue after discontinuation, according to a new study from researchers at the University of Colorado Anschutz Medical Campus. The study was published today in the journal PLOS ONE. “Despite the fact that benzodiazepines have been...
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Menopausal hormone therapy linked to increased rate of dementia
by British Medical Journal Credit: Pixabay/CC0 Public Domain Use of menopausal hormone therapy is associated with an increased rate of dementia and Alzheimer’s disease, suggests a large Danish study published by The BMJ. An increase was seen in long term users of menopausal hormone therapy, but also in short term users around the age of menopause (55...
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An unexpected doorway into the ear opens new possibilities for hearing restoration
UNIVERSITY OF ROCHESTER MEDICAL CENTER An international team of researchers has developed a new method to deliver drugs into the inner ear. The discovery was possible by harnessing the natural flow of fluids in the brain and employing a little understood backdoor into the cochlea. When combined to deliver a gene therapy that repairs inner ear hair...
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Cooperation between muscle and liver circadian clocks is key to controlling glucose metabolism, finds study
by Universitat Pompeu Fabra – Barcelona Credit: Cell Reports (2023). DOI: 10.1016/j.celrep.2023.112588 Collaborative work by teams at the Department of Medicine and Life Sciences (MELIS) at Pompeu Fabra University (UPF), University of California, Irvine (UCI), and the Institute for Research in Biomedicine (IRB Barcelona) has shown that interplay between circadian clocks in liver and skeletal muscle controls glucose metabolism. The...
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Study uncovers direct link between blood group A and a higher risk for COVID-19 infection
by American Society of Hematology Credit: Pixabay/CC0 Public Domain Ask the average American what their blood type is, and you will likely receive a blank look. For most people, blood type only becomes an issue if they need a blood transfusion. Beginning in the earliest days of the COVID-19 pandemic, however, results from previous work published in Blood Advances suggested...
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New competitor to Wegovy shows promise in clinical trials
by Dennis Thompson An experimental drug appears to outperform the trendy medications Wegovy and Ozempic for both weight loss and diabetes control, a pair of early clinical trials shows. Retatrutide helped people with obesity drop about one-quarter of their starting weight, on average, during 48 weeks taking the drug, according to phase 2 trial results published online...
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Research team achieves near-perfect bone healing with new multi-leveled scaffold
by Technical University of Denmark (a) Schematic representation of the (a) bone structure and its composition ranging from nanometers to micrometers and (b) development of biomimetic scaffolds containing the various steps for preparing a combinatorial hydrogel/scaffold. Credit: ACS Applied Materials & Interfaces (2023). DOI: 10.1021/acsami.3c01717 A team at DTU Health Tech, led by Associate Professor Alireza Dolatshahi-Pirouz, has...