By WASHINGTON UNIVERSITY SCHOOL OF MEDICINE APRIL 24, 2023 A study at Washington University School of Medicine in St. Louis has shown that the FDA-approved insomnia medication suvorexant may reduce key Alzheimer’s proteins in the brain. Participants who took a higher dose of the drug experienced a significant drop in amyloid and hyperphosphorylated tau levels. However, the...
Psoriasis – a common, chronic skin disease that affects over 100 million people worldwide. It is incurable, even though there are pretty effective techniques for managing the symptoms. However, now scientists from the University of Birmingham have discovered a protein, which could eventually lead to more effective therapies for many skin problems including psoriasis. This...
Surprising antibacterial activity and selectivity of hydrophilic phosphonium polymers WILEY Artificial polymers, like antibiotic peptides, need both hydrophobic and hydrophilic domains in their molecular structure to exert antibacterial activity. Now, researchers from Canada have synthesized a phosphonium polymer that challenges this view. As outlined in the journal Angewandte Chemie, their polymer salt contained no hydrophobic alkyl chains but...
PARP inhibitors show promise in preventing toxic accumulations of brain disease proteins in Penn research study UNIVERSITY OF PENNSYLVANIA SCHOOL OF MEDICINE PHILADELPHIA – A class of cancer drugs called PARP inhibitors could be useful for treating and preventing brain disorders, including amyotrophic lateral sclerosis (ALS), also called Lou Gehrig’s disease, and some forms of...
Several gene mutations have been linked to Parkinson’s disease, but exactly how and where some of them cause their damage has been unclear. A new Yale study, published in the Journal of Cell Biology, shows that one of the genes whose mutations are responsible for a familial form of Parkinson’s encodes a protein that controls the transfer...
A team of researchers from several institutions in Iceland and the U.S. has conducted a unique blood serum investigation and discovered multiple protein networks that are involved in the aging process. In their paper published in the journal Science, the group describes their study and what they found. Credit: Wikimedia Commons Prior research has shown that when older mice have...
BAYLOR COLLEGE OF MEDICINE Predicting genes that can cause disease due to the production of truncated or altered proteins that take on a new or different function, rather than those that lose their function, is now possible thanks to an international team of researchers, including researchers from Baylor College of Medicine, that has developed a new analytical tool...
AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY Aging is a process of gradual deterioration from exposure to time and the elements; this process begins with deterioration deep inside every cell. Researchers from Stanford University and the VA Palo Alto Health Care System (VAPAHCS) have identified a protein that guards cells against senescence – aging-related problems...
Study finds previously unknown strategy cells use to make protein CASE WESTERN RESERVE UNIVERSITY Scientists have long known that RNA encodes instructions to make proteins. The building blocks that comprise RNA–A, U, C, and Gs–form a blueprint for the protein-making machinery in cells. To make proteins, the machinery latches on RNA at one end and...
July 10, 2018, University of Maryland Baltimore County A team of researchers led by UMBC have developed a novel approach to making therapeutic proteins available at the point of care. This technology is unique because it ensures that medicines are available anywhere in the world, including remote locations, combat zones, and places impacted by natural disasters. A new paper...
