JUNE 5, 2024
by NYU Langone Health
Trichophyton indotineae causing tinea corporis. Credit: JAMA Dermatology (2024). DOI: 10.1001/jamadermatol.2024.1126
Health care providers should watch out for new and highly contagious forms of ringworm or jock itch, which are emerging as a potential public health threat, according to a pair of reports.
In the first of the studies, experts at NYU Langone Health who focus on the spread of contagious rashes document the first reported U.S. case of a sexually transmitted fungal infection that can take months to clear up even with treatment.
In the second report, NYU Langone physicians partnered with authorities at the New York State Department of Health to describe the largest group of patients in the country with a similar fungal strain that resists standard therapies.
Both species of fungi are among a group that causes skin rashes, or tinea, that easily spread on the face and limbs (ringworm), groin (jock itch), and feet (athlete’s foot). However, the tinea explored in the new reports can look very different from the neat, regular circles seen in most forms of ringworm. They may instead be confused for lesions caused by eczema and can therefore go without proper treatment for months.
The first report, published online on June 5 in the journal JAMA Dermatology, describes a man in his 30s who developed tinea on his penis, buttocks, and limbs after returning home to New York City from a trip to England, Greece, and California.
Genetic tests of fungal samples collected from the patient’s rashes revealed that the infection was caused by the species Trichophyton mentagrophytes type VII (TMVII). This sexually-transmitted form of ringworm has been increasingly diagnosed throughout Europe, with 13 instances reported in France in 2023, mostly in men who have sex with men. Notably, the man in the current study said he had sex with multiple male partners during his travels, none of whom reported similar skin issues.
“Health care providers should be aware that Trichophyton mentagrophytes type VII is the latest in a group of severe skin infections to have now reached the United States,” said study lead author and dermatologist Avrom Caplan, MD. Caplan is an assistant professor in the Ronald O. Perelman Department of Dermatology at NYU Grossman School of Medicine.
“Since patients are often reluctant to discuss genital problems, physicians need to directly ask about rashes around the groin and buttocks, especially for those who are sexually active, have recently traveled abroad, and report itchy areas elsewhere on the body,” added study senior author John Zampella, MD.
Zampella, an associate professor in the Ronald O. Perelman Department of Dermatology at NYU Grossman says that while infections caused by TMVII are difficult to treat and can take months to clear up, they so far appear to respond to standard antifungal therapies such as terbinafine.
Meanwhile, Caplan says the new skin condition explored in his other new report presents a greater challenge for dermatologists. The study results, published online in May in JAMA Dermatology, center on Trichophyton indotineae (T. indotineae), which is widespread in India and is now reported globally. First confirmed to be in the U.S. last year, the infection causes similar itchy and contagious rashes as TMVII but often resists terbinafine treatment.
More information: Potential Sexual Transmission of Tinea Pubogenitalis From TMVII, JAMA Dermatology (2024). DOI: 10.1001/jamadermatol.2024.1430
Caplan et al, Clinical Course, Antifungal Susceptibility, and Genomic Sequencing of Trichophyton indotineae, JAMA Dermatology (2024). DOI: 10.1001/jamadermatol.2024.1126
Journal information: JAMA Dermatology
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