Today’s open access review paper is a high level look at what the newfound realization of the importance of senescent cells to aging and age-related disease means for the treatment of chronic kidney disease. At present there are few good options for treatment, and those therapies that are widely used can only slow the progression towards kidney failure....
The article by Dr. Zatollah Asemi et al. is published in Current Pharmaceutical Design, Volume 24, Issue 31, 2018 BENTHAM SCIENCE PUBLISHERS Chronic Kidney disease (CKD) is highly associated with all-cause mortality, Diabetic Nephropathy (DN), cardiovascular events and hospitalization whether the patient has an existing risk or current cardiovascular disease or not. CKD can increase the chances of cardiovascular disease by two...
The kidney does more than double or even triple duty compared to other organs—it extracts waste, balances body fluids, forms urine, regulates blood pressure, and secretes hormones. Given this complexity, when things go wrong, havoc can ensue, causing a suite of symptoms called chronic kidney disease (CKD), which includes toxin accumulation, fatigue, and high blood...
Researchers working on a study to improve kidney function measurements have found a way to provide more accurate readings. Using an injectable biomarker, physicians were able to read the actual working capacity of the kidney in a clinical setting in half the time it used to take. Currently, physicians rely on estimated kidney function (or estimated glomerular filtration rate)...
Abstract Background: Complications of chronic kidney disease (CKD) include weak bones and increased fracture risk. Purpose: To review the benefits and harms of osteoporosis medications (bisphosphonates, teriparatide, raloxifene, and denosumab) compared with placebo, usual care, or active control in terms of bone mineral density (BMD), fractures, and safety in patients with CKD. Data Sources: PubMed...
