by Adam Pope, University of Alabama at Birmingham Credit: CC0 Public Domain Researchers with the University of Alabama at Birmingham Marnix E. Heersink School of Medicine have published a new study in PLOS ONE detailing a new therapy for acute exacerbations of idiopathic pulmonary fibrosis, or AE-IPF, that could potentially be lifesaving. Recent research studies have suggested...
UNIVERSITY OF ILLINOIS AT CHICAGO IMAGE: GEL-COATED (RED) MESENCHYMAL STROMAL CELLS (YELLOW) CAN DEGRADE COLLAGEN (GREEN) OVER A DISTANCE IN THE PRESENCE OF TUMOR NECROSIS FACTOR-ALPHA. CREDIT: JAE-WON SHIN AND SING-WAN WONG/UIC Researchers at the University of Illinois Chicago have shown that even after lung tissue has been damaged, it may be possible to reverse fibrosis and promote...
by Will Doss, Northwestern University Scott Budinger, MD, the Ernest S. Bazley Professor of Airway Diseases and chief of Pulmonary and Critical Care in the Department of Medicine, and Alexander Misharin, MD, PhD, assistant professor of Medicine in the Division of Pulmonary and Critical Care, were co- senior authors of the study published in PNAS. Credit: Northwestern...
ROCKEFELLER UNIVERSITY PRESS IMAGE: COMPARED WITH A CONTROL (LEFT), REMOVAL OF THE MDM4 GENE (RIGHT) FAVORS THE RESOLUTION OF FIBROTIC SCAR TISSUE IN THE LUNGS OF AGED MICE. CREDIT: ©2021 QU ET AL. ORIGINALLY PUBLISHED IN JOURNAL OF EXPERIMENTAL MEDICINE. HTTPS://DOI.ORG/10.1084/JEM.20202033 Researchers at the University of Alabama at Birmingham have identified a new molecular target that could potentially...
By Dr. Sanchari Sinha Dutta, Ph.D. Reviewed by Emily Henderson, B.Sc. Nail clubbing is characterized by specific changes around and under the toe and fingernails that are caused by certain diseases. Lung cancer is the most frequent cause of nail clubbing. What is nail clubbing? Nail clubbing, also called digital clubbing or Hippocratic nail, is...
CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) DEVELOPMENT OF THE INITIAL STAGES OF PULMONARY FIBROSIS ASSOCIATED WITH AGEING IN NON-TREATED MICE (LEFT), THAT CAN BE PREVENTED IN MICE TREATED WITH THE TELOMERASE GENE THERAPY (RIGHT). view more CREDIT: CNIO Idiopathic pulmonary fibrosis is a potentially lethal disease for which there is currently no cure and that...
(HealthDay)—Initiation of pulmonary rehabilitation within three months of hospital discharge for chronic obstructive pulmonary disease (COPD) is significantly associated with a lower risk for mortality at one year for Medicare beneficiaries, according to a study published in the May 12 issue of the Journal of the American Medical Association. Peter K. Lindenauer, M.D., from the...
by Charité – Universitätsmedizin Berlin CT images and tissue sections show how healthy, air-filled tissue is replaced by thickened, stiff connective tissue. Credit: Leitz/Charité Working alongside research groups from Heidelberg, researchers from Charité – Universitätsmedizin Berlin have elucidated the novel disease processes involved in the development of pulmonary fibrosis. They were able to show that...
A bacterial protein fragment instigates lung tissue death in pulmonary fibrosis, a mysterious disease affecting millions of people worldwide, according to a new study from researchers at the University of Illinois at Urbana-Champaign and Mie University in Japan. Led by Illinois microbiology and animal sciences professor Isaac Cann and Mie University immunology professor Dr. Esteban...
NORTH CAROLINA STATE UNIVERSITY A new study from North Carolina State University shows that lung stem cell secretions – specifically exosomes and secretomes – delivered via nebulizer, can help repair lung injuries due to multiple types of pulmonary fibrosis in mice and rats. The work could lead to more effective, less invasive treatment for human...
