By Sally Robertson, B.Sc. A study conducted by researchers in the UK and Italy suggests that individuals with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are probably at their most infectious during the first week of illness. The systematic review and meta-analysis of data available on the viral dynamics of SARS-CoV-2 found that although viral...
This news or article is intended for readers with certain scientific or professional knowledge in the field. A new multi-institution, dose-determining clinical trial of a compound against metastatic, castration-resistant prostate cancer showed promising results, researchers reported in Clinical Cancer Research. The phase 1b/2a study of the pan-BET bromodomain inhibitor ZEN-3694 in combination with enzalutamide was...
This news or article is intended for readers with certain scientific or professional knowledge in the field. Enzalutamide is one of the main treatments for patients with metastatic, castration-resistant prostate cancer — the lethal form of the disease. However, treatment options are limited for those who develop resistance to enzalutamide. Now, a multi-institution team has...
UNIVERSITY OF MAINE Jared Talbot is part of a 32-member international research team that identified a gene that, when altered, can cause bent fingers and toes, clubfoot, scoliosis, and short stature. The team discovered that partial loss of the protein coding gene MYLPF (myosin light chain, phosphorylatable, fast skeletal muscle) results in a disorder called...
Antibiotic-resistant diabetic foot ulcer application FLINDERS UNIVERSITY Australian researchers have shown how viruses can be used to save lives, developing the potential use of bacteriophages in bandages to treat life-threatening golden staph infections which may not respond to traditional antibiotics. Targeting multidrug-resistant Staphylococcus aureus (‘golden staph’) in diabetic foot ulcers, Flinders University microbiology researchers have...
by John Innes Centre Compounds tested for their potential as antibiotics have demonstrated promising activity against one of the deadliest infectious diseases—tuberculosis (TB). Researchers from the John Innes Centre evaluated two compounds with antibacterial properties, which had been produced by the company Redx Pharma as antibiotic candidates, particularly against TB. TB, which is caused by...
by Macquarie University Researchers from Macquarie University have discovered a world-first new treatment that reverses the effects of memory loss associated with Alzheimer’s disease in a study of mice with advanced dementia. The research, co-led by two brothers, Dr. Arne Ittner and Professor Lars Ittner, from Macquarie University Dementia Research Center, builds on their work...
by Barbara Branning, University at Buffalo The findings from a recent study by a University at Buffalo researcher and others could prove to be a game-changer for men with Type 2 diabetes. The single-site study, conducted over 11 years in Bremerhaven, Germany, found that testosteronetherapy reversed Type 2 diabetes in a one-third of the study...
by Wellcome Trust Sanger Institute A study has revealed that tumors can evade the immune system by telling immune cells to produce immunosuppressive steroids. Researchers from the Wellcome Sanger Institute, Department of Pathology, University of Cambridge, and MRC Cancer Unit, discovered that immune T cells from mouse skin and breast tumors secrete steroids, and that...
An update to the Lancet Commission on dementia prevention, intervention and care adds excessive alcohol intake, head injury and air pollution to nine previously identified modifiable risks IMAGE: MODIFYING 12 RISK FACTORS OVER A LIFETIME COULD DELAY OR PREVENT 40% OF DEMENTIA CASES. CREDIT: COURTESY OF KECK MEDICINE OF USC LOS ANGELES — Modifying 12...
