TOKYO UNIVERSITY OF SCIENCE IMAGE: Scientists from Japan and the United States have identified a new mechanism of blood-brain barrier degradation in the post-stroke brain, involving acrolein-induced modifications of proheparanase. This discovery could lead to the production of newer and more effective drugs for stroke-related disorders. CREDIT: TOUBIBE FROM PIXABAY Strokes are a leading cause...
Texas A&M-UTMB team identifies potential drug to treat SARS-CoV-2
TEXAS A&M UNIVERSITY A federally approved heart medication shows significant effectiveness in interfering with SARS-CoV-2 entry into the human cell host, according to a new study by a research team from Texas A&M University and The University of Texas Medical Branch (UTMB). The medication bepridil, which goes by the trade name Vascor, is currently approved by the...
Neural pathway critical to correcting behavioral errors related to psychiatric disorders found
by The Mount Sinai Hospital Credit: The Mount Sinai Hospital Mount Sinai researchers have identified a neural pathway through which the brain detects errors and guides subsequent behavioral improvement. This process, called cognitive control, is frequently dysregulated in a wide range of psychiatric disorders. The team’s research, published February 19 in Neuron, also suggests that neurostimulation of this brain pathway...
Long-term stress linked to increased risk of heart attack
Can long-term stress lead to heart attacks? Most people would probably answer in the affirmative, but the scientific evidence of this is scarce. A new study reveals that the levels of the stress hormone cortisol were increased in the months preceding a heart attack. The results suggest that long-term stress is a risk factor for...
Study estimates two-thirds of COVID-19 hospitalizations due to four conditions
TUFTS UNIVERSITY, HEALTH SCIENCES CAMPUS IMAGE: STUDY SUGGESTS COVID-19 HOSPITALIZATIONS COULD HAVE BEEN PREVENTED WITHOUT FOUR COMMON PRE-EXISTING CONDITIONS. CREDIT: GERALD J. AND DOROTHY R. FRIEDMAN SCHOOL OF NUTRITION SCIENCE AND POLICY AT TUFTS UNIVERSITY A modeling study suggests a majority of adult COVID-19 hospitalizations nationwide are attributable to at least one of four pre-existing...
Experimental treatment appears to subdue type 1 diabetes in laboratory mice
by University of Utah Health Sciences Credit: Unsplash/CC0 Public Domain An experimental treatment can essentially reverse type 1 diabetes in certain types of laboratory mice, according to a series of studies led by University of Utah Health scientists. An injection of the therapeutic agent converts cells that normally control glucose production into ones that generate insulin....
New drug molecules hold promise for treating fatal child disease
by University of Exeter Histopathology of gastrocnemius muscle from patient who died of pseudohypertrophic muscular dystrophy, Duchenne type. Cross section of muscle shows extensive replacement of muscle fibers by adipose cells. Credit: Public Domain Scientists have identified a way to “rescue” muscle cells that have genetically mutated, paving the way to a possible new treatment for...
MDMA proves a promising alcoholism treatment in world
By Rich Haridy February 21, 2021 A proof-of-concept study found MDMA therapy for alcohol use disorder to be safe and potentially effective at reducing drinking behaviorsfocuspocusltd/Depositphotos A new study published in the Journal of Psychopharmacology is reporting on a landmark clinical trial exploring the potential for MDMA-assisted psychotherapy in treating subjects with alcohol use disorder. The small...
Magnetic attraction: breakthrough test for malaria
Dr Stephan Karl, a Senior Research Fellow in Malaria and Vector Biology at James Cook University’s Australian Institute of Tropical Health and Medicine, has led an international study to field-test a new tool in the fight to eliminate the disease, which had 229 million reported cases in 2019. “Malaria is easily treated but it is actually hard...
Store Fat or Burn It? Targeting a Single Protein Flips the Switch
As obesity becomes a growing issue worldwide – nearly tripling over the last-half century – scientists are trying to gain a better understanding of the condition at the molecular level. Now, new research led by UC San Francisco scientists suggests that a single protein could play an outsized role in weight gain. As reported in Nature Metabolism, UCSF’s Davide...