by American Heart Association Credit: Pixabay/CC0 Public Domain The same risk factors that contribute to making heart disease the leading cause of death worldwide also impact the rising global prevalence of brain disease, including stroke, Alzheimer’s disease and dementia, according to the American Heart Association’s Heart Disease and Stroke Statistics—2022 Update, published today in the...
Physical activity protects against type 2 diabetes by modifying metabolism
by University of Eastern Finland Figure 1. The association of physical activity (PA) changes with glucose and insulin concentrations, insulin sensitivity, and insulin secretion in 5867 participants without diabetes at baseline, subjected to oral glucose tolerance tests both at baseline and follow-up visits. The effect sizes (β, SE) are given as the standardized mean differences...
Active ingredient in cannabis protects aging brain cells
by Salk Institute Healthy mitochondria (green); mitochondria showing the effects of oxidative stress (blue); and oxidative stress with CBN (red). Insets show higher magnification of the structure of the mitochondria. Credit: Salk Institute Decades of research on medical cannabis has focused on the compounds THC and CBD in clinical applications. But less is known about...
Gene expression could ring early kidney disease alarm
by Michaela Kane, Duke University Podocyte Models. Credit: Duke University Biomedical engineers at Duke University have developed a method to study how key cells in the kidneys become injured and deformed. The new model has revealed a significant mechanism behind severe kidney disease and pointed toward early disease biomarkers and potential therapeutic interventions. The study...
EEG analysis may detect up to 99.5 percent of concussions
by Scott Schrage, University of Nebraska-Lincoln Analyzing certain frequencies of brain activity via EEGs could help monitor athletes for concussions that might otherwise go overlooked or unreported, according to a new study from Husker researchers. Credit: Shutterstock / Scott Schrage | University Communication A linebacker gets blindsided by a block, helmets colliding before the defender...
Macromolecular gel with therapeutic payload could be silver bullet for osteoarthritis
by NYU Tandon School of Engineering Credit: Shutterstock Osteoarthritis affects over 32 million Americans, levies a huge cost on society, and vastly increases one’s chances of developing heart disease. Unfortunately, other than analgesics no pharmaceutical therapy exists that can slow or halt disease progression of a major subset of OA: post-traumatic osteoarthritis (PTOA). PTOA, a...
Chronic marijuana use negatively impacts male reproductive health, may decrease testicular function
by Tracy Brawley, Oregon Health & Science University Credit: CC0 Public Domain Chronic use of marijuana may greatly impact male fertility and reproductive outcomes, says a new report published online in the journal Fertility & Sterility. The study is the first to assess the impacts of substance use on testicular function via a mode of delivery, and...
Researchers develop new clinical diagnostic test to identify genetic sources of mitochondrial disease
by Children’s Hospital of Philadelphia Structure of the human mitochondrial genome. Credit: Wikipedia/CC BY-SA 3.0 Researchers from the Mitochondrial Medicine Frontier Program at Children’s Hospital of Philadelphia (CHOP) have developed a comprehensive sequencing test specifically for mitochondrial DNA (mtDNA). This new clinical diagnostic test, launched in the Division of Genomic Diagnostics (DGD) at CHOP, provides...
New research links genes to a longer human lifespan
by University College London Credit: Pixabay/CC0 Public Domain A group of genes that play an essential role in building components of our cells can also impact human lifespan, finds a new study led by UCL researchers. The genes have previously been found to extend lifespan in small organisms, such as making fruit flies live 10%...
Migraine Comorbidities: What You Need to Know
Dawn C. Buse, Ph.D.; Richard Lipton, MD January 06, 2022 Being knowledgeable about comorbidities is essential to the study and management of migraine. Migraine is the second most disabling condition worldwide, and comorbidities contribute to disease burden, decrease health-related quality of life, and add to economic burden. Identification of migraine comorbidities can help determine diagnosis, improve the ability to assess...