GEORGIA STATE UNIVERSITY ATLANTA—The pandemic has taken a substantial toll on mental health — and for a subset of Americans, COVID has emerged as a source of traumatic stress that may predict post-traumatic stress disorder, or PTSD, according to a new study led by Georgia State University. The research shows that the association between COVID traumatic stress...
Gene Therapy for the Treatment of Huntington’s Disease
MARY ANN LIEBERT, INC./GENETIC ENGINEERING NEWS IMAGE: THE FIRST PEER-REVIEWED JOURNAL IN THE FIELD AND PROVIDES ALL-INCLUSIVE ACCESS TO THE CRITICAL PILLARS OF HUMAN GENE THERAPY: RESEARCH, METHODS, AND CLINICAL APPLICATIONS. CREDIT: MARY ANN LIEBERT INC., PUBLISHERS Gene therapy targeting the messenger RNA (mRNA) of the mutated huntingtin gene (HTT) can provide long-lasting therapeutic benefit...
Antibody with engineered peptide targets bone metastasis
by Mike Williams, Rice University Rice scientists added a bone-targeting peptide to an antibody used to fight breast cancer to curtail metastasis to the bone. Credit: Xiao Research Group A moderate amount of a peptide-enhanced, biological cancer drug goes a long way in treating breast cancers that metastasize to the bone. A study by scientists...
Fast, cheap test can detect COVID-19 virus’s genome without need for PCR
by James Urton, University of Washington The Harmony COVID-19 test includes a small, inexpensive detector (left) that can processes four reaction tubes—shown in the detector—and a sample collection device (center). Results are displayed on a smartphone (right). Credit: Mark Stone/University of Washington Researchers at the University of Washington have developed a new test for COVID-19...
FDA halts use of antibody drugs that don’t work vs. omicron
by Matthew Perrone A doctor holds a Regeneron monoclonal antibody infusion bag during a news conference Thursday, Aug. 19, 2021 at a hospital in Fort Lauderdale, Fla. On Monday, Jan. 24, 2022, the Food and Drug Administration said COVID-19 antibody drugs from Regeneron and Eli Lilly should no longer be used because they are unlikely...
Seeing the same GP improves treatment for people with dementia, study finds
by University of Exeter Credit: CC0 Public Domain People with dementia who see the same GP each time have lower rates of health complications and fewer emergency hospital admissions, according to a new study. The research, led by the University of Exeter and published in the British Journal of General Practice (BJGP) analyzed more than 9,000patient records...
Contrary to the common view, cerebral palsy can be genetic
by Children’s Hospital Boston Credit: CC0 Public Domain Cerebral palsy, a non-progressing motor impairment that begins in early childhood, has widely been viewed as the result of oxygen deprivation during birth or other birth-related factors such as prematurity. While this is true for many children, new research from Boston Children’s Hospital finds that as many...
Transcranial ultrasound used in mice with Alzheimer’s disease features
by Alzheimer’s Research UK Experiment protocol. (a) EEG electrode positions for surgical implantation. E1 and E2 indicate electrodes on the frontal and parietal cortex, respectively, while reference electrode (R) was placed on cerebellum. G and A correspond to the electrodes for animal grounding and the anchoring screw, respectively. Red dots denote the location of implants...
Is omicron infection inevitable?
by Kathy Katella, Yale University Credit: Unsplash/CC0 Public Domain Omicron, the latest SARS-CoV-2 variant, is spreading like wildfire across the country. Some experts say it is so transmissible that many people, including those who are vaccinated and boosted, are likely to get it. That is worrisome news, especially to parents of children who are not...
Novel therapeutic approach to tackle obesity shows promise in lab trials
by Nanyang Technological University The therapeutic approach developed by NTU Singapore starts with an injection of a specially developed hydrogel using an insulin needle, into a fat deposit directly under the skin. After the hydrogel is injected, near infrared light is then shone on the site of injection. This activates the gel’s fat-burning ability. Credit:...