Month: <span>January 2022</span>

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Identifying the neural network responsible for how tics develop
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Identifying the neural network responsible for how tics develop

by Charité – Universitätsmedizin Berlin On this brain scan image, colored areas denote parts of the neural network which is capable of generating tics. Credit: Charité | Bassam Al-Fatly A team of researchers from Charité – Universitätsmedizin Berlin has identified a neural network which is responsible for generating tic disorders. Targeting of this network via deep brain...

Engineers are working on a new device that could streamline blood glucose measurement and insulin
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Engineers are working on a new device that could streamline blood glucose measurement and insulin

by Anne Trafton, Massachusetts Institute of Technology MIT engineers are working on an app that identifies and quantifies food content, which can aid in carbohydrate counting for people with diabetes. Credit: MIT News, stock images Before consuming a meal, many people with diabetes need to inject themselves with insulin. This is a time-consuming process that...

Predicting long COVID at initial point of COVID-19 diagnosis
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Predicting long COVID at initial point of COVID-19 diagnosis

by Institute for Systems Biology  Credit: Pixabay/CC0 Public Domain A significant portion of people who contract the SARS-CoV-2 virus—some estimates suggest more than 40 percent—suffer chronic effects known as Post Acute Sequelae of COVID-19 (PASC), commonly referred to as long COVID. PASC symptoms include fatigue, brain fog, the loss of taste and smell, shortness of...

Like tiny drill sergeants, neurons identified in spinal cord coordinate our steps
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Like tiny drill sergeants, neurons identified in spinal cord coordinate our steps

by Columbia University Irving Medical Center Credit: Public Domain Walking is the most natural of movements. Without thinking, we put one foot forward and then the next, on and on, propelling us forward. So, if we’re not consciously directing this complex interplay of nerves and muscles, what is? “As one might expect, it’s the brain...

Scientists unveil world’s first molecular-level analysis of Omicron spike protein
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Scientists unveil world’s first molecular-level analysis of Omicron spike protein

by University of British Columbia Atomic structure of the Omicron variant spike protein (purple) bound with the human ACE2 receptor (blue). Credit: UBC Faculty of Medicine Researchers at UBC’s faculty of medicine have conducted the world’s first molecular-level structural analysis of the Omicron variant spike protein. The findings were published today in Science. The analysis—done at...

Study illustrates links between DNA repair and a rare neurodegenerative disease
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Study illustrates links between DNA repair and a rare neurodegenerative disease

by The Francis Crick Institute A depiction of the double helical structure of DNA. Its four coding units (A, T, C, G) are color-coded in pink, orange, purple and yellow. Credit: NHGRI Researchers at the Francis Crick Institute have pieced together genetic and molecular changes that lead to a rare progressive neurodegenerative condition called ataxia...

Multi-organoid system to simulate human liver-islet axis in normal and type 2 diabetes
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Multi-organoid system to simulate human liver-islet axis in normal and type 2 diabetes

by Li Yuan, Chinese Academy of Sciences Schematic of hiPSCs derived multi-organoid-on-chip system to model human liver-pancreatic islet axis in vitro. Credit: Tao Tingting Type 2 diabetes (T2DM) is a systematic multi-organ metabolic disease, which is characterized by dynamic interplay among different organs. Pancreatic islet-liver axis is closely associated with normal glucose regulation and homeostasis...

Researchers discover way to disarm potentially deadly Listeria bacteria
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Researchers discover way to disarm potentially deadly Listeria bacteria

by University of Queensland A drug-like inhibitor that stops Listeria from making virulence proteins helps immune cells control and kill the bacteria. Credit: Dr Carmen Mathmann University of Queensland researchers have unlocked a way of fighting Listeria infections, which can cause severe illness in pregnant women and people with compromised immune systems. During the study,...

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Relatlimab Plus Nivolumab a ‘Game Changer’ in Advanced Melanoma

Megan Brooks January 05, 2022 For untreated advanced melanoma, the fixed-dose combination of relatlimab and nivolumab is a “game changer that we have been waiting 10 years for,” Hussein Tawbi, MD, PhD, University of Texas MD Anderson Cancer Center, Houston, told Medscape Medical News about today’s publication of the phase 2/3 RELATIVITY-047 trial. Progression-free survival (PFS) was “essentially double” with...

Brain damage markers greater in people with severe COVID-19 than those with Alzheimer’s
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Brain damage markers greater in people with severe COVID-19 than those with Alzheimer’s

Healthcare worker Demetra Ransom comforts a person with COVID-19 at United Memorial Medical Center in Houston, Texas, on December 4, 2020. MARK FELIX/Getty Images A study demonstrated that participants hospitalized with COVID-19 experiencing neurological complications had higher levels of blood proteins or biomarkers associated with neurological damage than people with Alzheimer’s. Increased biomarker levels correlated...