Month: <span>January 2022</span>

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Difference between retina’s biological age and person’s real age linked to heightened death risk
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Difference between retina’s biological age and person’s real age linked to heightened death risk

by British Medical Journal Credit: Unsplash/CC0 Public Domain The difference between the biological age of the retina, the light sensitive layers of nerve tissue at the back of the eye, and a person’s real (chronological) age, is linked to their risk of death, finds research published online in the British Journal of Ophthalmology. This ‘retinal age...

Astrocyte studies reveal harmful changes in Amyotrophic Lateral Sclerosis
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Astrocyte studies reveal harmful changes in Amyotrophic Lateral Sclerosis

by The Francis Crick Institute An MRI with increased signal in the posterior part of the internal capsule which can be tracked to the motor cortex consistent with the diagnosis of ALS. Credit: Frank Gaillard/Wikipedia Scientists at the Francis Crick Institute have revealed harmful changes in supporting cells, called astrocytes, in Amyotrophic Lateral Sclerosis (ALS)...

Without coronary calcium, risk factors impact cardiovascular disease
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Without coronary calcium, risk factors impact cardiovascular disease

by Will Doss, Northwestern University Credit: Unsplash/CC0 Public Domain Among patients with no detectable coronary artery calcium, those who smoke, have diabetes or hypertension nonetheless have the highest risk of cardiovascular disease events, according to a study published in the journal Circulation. The findings demonstrate that even in patients with no coronary artery calcium, the traditional...

Early prostate cancers can harbor aggressive tumor cells
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Early prostate cancers can harbor aggressive tumor cells

by Sarah Avery, Duke University Micrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia Many cases of early prostate cancer are dominated by cells that are slow-growing, often leading to a clinical decision to monitor for progression before initiating treatments that can have adverse side effects. But some of these...

Using a bacteriophage to successfully treat a patient infected with a drug-resistant bacteria
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Using a bacteriophage to successfully treat a patient infected with a drug-resistant bacteria

by Bob Yirka, Medical Xpress Relevant genomic and proreomic characteristics of phage M1. Genome representation of phage M1 and comparison, using a BLASTn analysis, with Slopekvirus type species KP15 (a). Each white or colored arrow represents a predicted open reading frame. In orange, genes encoding packaging and lysis-associated proteins are displayed, in yellow structural proteins...

The epigenetic mechanism by which vitamin D modulates the tolerance of the immune system
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The epigenetic mechanism by which vitamin D modulates the tolerance of the immune system

by Josep Carreras Leukaemia Research Institute Dr. Esteban Ballestar at the Josep Carreras Leukaemia Research Institute. Credit: Josep Carreras Leukaemia Research Institute In autoimmunity, the mechanisms that guarantee that our defense system does not attack our own body—tolerance to oneself—does not work properly. Multiple sclerosis, which affects one in every 1,000 people in Spain, is...

New AI model helps discover causes of motor neurone disease
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New AI model helps discover causes of motor neurone disease

by University of Sheffield Credit: Pixabay/CC0 Public Domain Scientists have developed a new machine learning model for the discovery of genetic risk factors for diseases such as Motor Neurone Disease (MND). Designed by researchers from the University of Sheffield and the Stanford University School of Medicine in the US, the machine learning tool, named RefMap,...

Multifunctional bioactive components screened out from herbal medicine using multi-target ultrafiltration
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Multifunctional bioactive components screened out from herbal medicine using multi-target ultrafiltration

by Zhang Nannan, Chinese Academy of Sciences The constructed multi-component and multi-target network incorporating the potential bioactive components screened out with multiple drug targets. Credit: WBG Podophyllum sinense, a folk herbal medicine, possesses multiple phytochemicals and extensive pharmaceutical activities. Modern pharmacological studies have indicated that P. sinense has remarkable activities, such as anti-proliferative, anti-inflammatory, anti-viral...

Placebo effect accounts for more than two-thirds of COVID-19 vaccine adverse events
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Placebo effect accounts for more than two-thirds of COVID-19 vaccine adverse events

by Beth Israel Deaconess Medical Center A medical assistant prepares a dose of a COVID-19 vaccine to be administered to a patient. Credit: Public domain image courtesy of Lisa Ferdinando, U.S. Department of Defense The placebo effect is the well-known phenomenon of a person’s physical or mental health improving after taking a treatment with no...

Neutral mutants can prevail in gut microbiota, enhancing diversity
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Neutral mutants can prevail in gut microbiota, enhancing diversity

by Nik Papageorgiou, Ecole Polytechnique Federale de Lausanne Fate of neutral mutants appearing at various locations in the gut. (A) Steady-state ratio M / B of mutant to wild-type bacteria concentrations and number of reproduction events R per unit volume and unit time vs. position xM of the mutant introduction. The ratio M / B yields...