by University of Seville Fig. 1. Generation of NrxnCTF transgenic mice. A) Schematic drawings showing the proteolytic processing of Nrxns by metalloproteases and PS (left) and the HA-tagged NrxnCTF transgene used in this study (right). The regions recognized by the HA and the cyto-Nrxn antibodies are indicated. LNS, Laminin/Neurexin/Sex hormone binding-globulin domain; TM, transmembrane region....
By Michael Irving January 17, 2022 A new technique can sequence a person’s entire genome and diagnose genetic disease in just a few hours SSilver/Depositphotos Genome sequencing can be used to determine whether a patient’s illness is genetic, but it usually takes weeks to get results. A new ultra-rapid technique can sequence a person’s genome...
Viruses that infect bacteria could one day replace antibiotics because they precisely attack only specific pathogens. Researchers at ETH Zurich are now showing that this is not always the case. This new finding is important because bacterial viruses can transfer antibiotic resistance genes. Bacteriophages – phages for short – are viruses that infect only bacteria. To capture...
By Angus Chen Jan. 14, 2022 MOLLY FERGUSON FOR STAT CAR-T cell therapy has been a boon for treating blood cancers. Since the technology was first brought to the clinic, CAR-T has offered patients months or years of life after they had exhausted all other treatment options and would have died within weeks. “It’s been...
JANUARY 17TH, 2022 CONN HASTINGS MEDICINE, NANOMEDICINE Researchers at the University of Pennsylvania School of Medicine have created a new coating for nanoparticles that can help to protect them from attacks by the immune system. The approach, which uses naturally occurring proteins that can inhibit the complement system, can significantly reduce immune destruction of nanoparticles, meaning that more...
MEDICAL UNIVERSITY OF VIENNA It is important that multiple sclerosis (MS) is diagnosed and treated as early as possible in order to delay progression of the disease. The technique of magnetic resonance imaging (MRI) plays a key role in this process. In the search for ever better methods, a new MRI technique has been used...
WASHINGTON STATE UNIVERSITY One viral protein could provide information to deter pneumonia causing the body’s exaggerated inflammatory response to respiratory viruses, including the virus that causes COVID-19. That viral protein is NS2 of Respiratory Syncytial Virus (RSV), and a study has found that if the virus lacks this protein, the human body’s immune response can...
UNIVERSITY HOSPITALS CLEVELAND MEDICAL CENTER IMAGE: “OUR GOAL IS TO BETTER PERSONALIZE THERAPY FOR PROSTATE CANCER PATIENTS, BY PROVIDING THE MOST PRECISE AND ACCURATE ESTIMATES OF THE BENEFIT OF HORMONE THERAPY.” ~ SENIOR AUTHOR, DANIEL E. SPRATT, MD. CREDIT: UNIVERSITY HOSPITALS CLEVELAND–Prostate cancer is the leading cause of cancer in men worldwide, and radiotherapy is...
JANUARY 17, 2022 by Lund University Figure 1. Convalescent patient plasma reduces Spike-monocyte interaction. (A) Biotinylated Spike protein was conjugated to fluorescent (APC) streptavidin microspheres and was opsonized with three convalescent patient plasma concentrations (1%, 0.1%, and 0.01%). The beads were then mixed with THP-1 cells at a ratio of 2:1, and the association was measured using...
JANUARY 17, 2022 by Josef Federman Siblings wait to receive the COVID-19 vaccine at Clalit Health Services in Mevaseret Zion, Tuesday, Jan. 11, 2022. Credit: AP Photo/Maya Alleruzzo An Israeli hospital on Monday said preliminary research indicates a fourth dose of the coronavirus vaccine provides only limited defense against the omicron variant that is raging...
