Cornell researchers have for the first time successfully imaged the entire depth of the lymph nodes in a living mouse using three-photon microscopy. The breakthrough technique’s micrometer clarity and noninvasive nature allowed the team to observe the dynamic interactions of immune cells in real time and in an environment that is notoriously dense and difficult...
Month: <span>January 2022</span>
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New blood test combined with image-based prostate cancer screening reduces harms and costs
The combination of a novel blood test and magnetic resonance imaging (MRI) can reduce overdiagnosis of low-risk cancers as well as societal costs in prostate cancer screening, according to a cost-effectiveness study from Karolinska Institutet published in the journal European Urology. The results provide support for organised prostate cancer testing in Sweden, researchers say. A barrier to...
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2 rheumatoid arthritis drugs tied to lower risk of Parkinson’s
(HealthDay)—Two rheumatoid arthritis drugs show potential for lowering the risk of Parkinson’s disease, new research shows. Some previous studies have found that people with rheumatoid arthritis have a lower risk of Parkinson’s, and it was suggested that a class of rheumatoid arthritis drugs called disease-modifying antirheumatic drugs (DMARDs) may play a role in that reduced...
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Blocking sphingolipids counteracts muscular dystrophy
by Ecole Polytechnique Federale de Lausanne Staining of a skeletal muscle cross-section showing different types of muscle fiber in young mice. Green: slow-twitch fibers type I; Red: Intermediate fast-twitch fibers type IIA; Purple: Very fast-twitch fibers type IIB; Yellow: Laminin. Credit: Martin Wohlwend (EPFL) EPFL scientists have made the first link between muscular dystrophy and...
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Pioneering University of Limerick, Ireland professor of surgery sheds light on a new order in the abdomen
by University of Limerick J Calvin Coffey, Foundation Chair of Surgery at UL’s School of Medicine in Ireland, whose major discovery led to the reclassification of the mesentery as a new organ in 2016, has published new research on the makeup and structure of the abdomen. Credit: Alan Place A pioneering University of Limerick professor...
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Lung abnormalities found in long COVID patients
by University of Sheffield Credit: Pixabay/CC0 Public Domain Researchers have identified abnormalities in the lungs of long COVID patients who are experiencing breathlessness that cannot be detected with routine tests. The EXPLAIN study, which involves teams at Sheffield, Oxford, Cardiff and Manchester, is using hyperpolarised xenon MRI scans to investigate possible lung damage in long...
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An electrically charged thin film patch used to promote wound healing
by Bob Yirka, Medical Xpress FIG. 1. Working principle and characterization of the EMSD.(A) Schematics of the overall EMSD-L and EMSD-C (top). Exploded illustration of the device components, essential materials, and multilayer structures (bottom). (B) Working principle of wound treatment by programmable and skin temperature–activated EMSDs. (C) Optical images of the initial state (left), twisted...
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Stool samples reveal microbial enzyme driving bowel disease
by Nicole Mlynaryk, University of California – San Diego The presence of Bacteroides vulgatus led to colitis in the mouse colon (left). However, protease inhibition protected the walls of the colon and reduced influx of inflammatory cells (right). Credit: University of California – San Diego Ulcerative colitis, a subtype of inflammatory bowel disease, is a...
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Intranasal flu vaccine with nanoparticles offers robust protection, researchers find
by Georgia State University Credit: Pixabay/CC0 Public Domain An influenza vaccine administered through the nose and constructed with nanoparticles that enhance immune response offers strong protection against different influenza virus strains, according to researchers in the Institute for Biomedical Sciences at Georgia State University. The intranasal vaccine contributed to multifaceted immune responses, leading to robust cross protection...
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In ‘chemo brain,’ researchers see clues to unravel long Covid’s brain fog
By Elizabeth Cooney Jan. 28, 2022 Stanford neuro-oncologist Michelle Monje is studying the link between “chemo brain” and long Covid’s brain fog. Back in the pandemic’s first wave, Michelle Monje was worried about Covid-19’s power to muddle the brain. Seeing the massive inflammatory response to the virus and early signs of what became known as...