By Elizabeth Cooney Jan. 28, 2022 Stanford neuro-oncologist Michelle Monje is studying the link between “chemo brain” and long Covid’s brain fog. STANFORD Back in the pandemic’s first wave, Michelle Monje was worried about Covid-19’s power to muddle the brain. Seeing the massive inflammatory response to the virus and early signs of what became known...
Long COVID Linked to Unbalanced Gut Microbiome: What to Know Now
Miodrag Ignjatovic/Getty Images Long COVID is a condition that involves persistent symptoms for weeks or months after initial infection with SARS-CoV-2, the coronavirus that causes COVID-19. People with a less diverse microbiome in their intestines were more likely to have lingering symptoms after coronavirus infection. The exact cause of long COVID — and why some...
Ketamine an ‘Intriguing New Therapy’ for Alcoholism
Megan Brooks January 25, 2022 Three weekly infusions of the dissociative anesthetic ketamine coupled with mindfulness-based relapse prevention therapy may help adults with alcohol use disorder (AUD) maintain abstinence, new research suggests. Preliminary results from a phase 2, double-blind, placebo-controlled trial show ketamine was well tolerated and, compared with placebo, associated with more days of...
How mRNA and DNA vaccines could soon treat cancers, HIV, autoimmune disorders and genetic diseases
January 24, 2022 8.31am EST Author Deborah FullerProfessor of Microbiology, School of Medicine, University of Washington The two most successful coronavirus vaccines developed in the U.S. – the Pfizer and Moderna vaccines – are both mRNA vaccines. The idea of using genetic material to produce an immune response has opened up a world of research...
Artificial muscles made of proteins
by University of Freiburg Scheme of the artificial protein muscle design, fabrication, and application. a) Natural muscle characteristics. Inspired by nature’s high-performance materials elastin and resilin. b) Novel protein genes are designed to biotechnologically produce the corresponding recombinant proteins. c) Yielding a pH-responsive protein (DSY)16 d) upper sequence in red) and a temperature-responsive protein (VRY)16...
Simple and reliable ALS diagnosis with blood tests
by University of Gothenburg Biomarker correlation to survival, survival analyses in clinical symptom onset and genotype groups, biomarker ratios and ALSFRS-R in ALS patients. (A) Correlation between plasma NFL and survival after symptom onset stratified by spinal and bulbar symptom onset. (B) Kaplan–Meier survival analysis for spinal onset versus bulbar onset ALS patients. (C) Correlation...
New vaccine may provide better treatment for tuberculosis
by University of Oslo Credit: Unsplash/CC0 Public Domain A new vaccine against tuberculosis may also be used as treatment. The vaccine is safe to give to people with tuberculosis disease and strengthens the immune system’s ability to attack the bacteria that cause the disease, a new study shows. Tuberculosis is an infectious disease caused by the tubercle...
Creating non-hallucinogenic analogs of LSD and psilocybin to treat mental illnesses
by Bob Yirka, Medical Xpress Effects of the psychedelics on animal behavior relevant to hallucination and depression. (A) Effect of LSD, lisuride, psilocin, and DOI on HTR behavior in mice (30- to 60-min time interval, Related Fig. S8A-D). (B) Metabolic rate and brain penetration of IHCH7079/7086/7113 in C57/BL6J mice (5 mg/kg intraperitoneally (ip); n =...
Retrotransposon expression is repressed in Huntington’s disease
by John Hewitt, Medical Xpress Figure 1. Differentially expressed TEs. (A) Volcano plot showing the murine TE consensus sequences differentially expressed in the striatum of 2-, 6-, and 10-mo mice in Q111 and Q175 genotypes compared to control (Q20). Blue color indicates the TE consensus sequences that result downregulated in each tested comparison (Q111 vs....
Virtual reality game can assess children’s ADHD symptoms
By simulating the challenges of everyday life, a new VR game can help diagnose and perhaps treat ADHD. A new virtual reality game helps detect symptoms related to attention deficit hyperactivity disorder (ADHD) in children, which has been challenging with the existing tools. With further work, the game could also help treat ADHD, as well as...