by University of California – San Diego Credit: Pixabay/CC0 Public Domain By analyzing disease mechanisms in human neurons, researchers led by the University of California San Diego developed a new method to screen drugs for treating Alzheimer’s disease. Their work sheds light on why Alzheimer’s drugs so far have been ineffective at curing or reversing...
by University of California, Irvine “AdipoR1 is one of the principal enzymes that regulate ceramide content in the eye,” says first and co-corresponding author Dominik Lewandowski, Ph.D., postdoctoral scholar at the UCI School of Medicine. “Ceramide accumulation is detrimental for the retina and has been associated with non-syndromic retinitis pigmentosa. Our study showed that this...
by Bhanu Sharma, The Conversation Concussion patients were once prescribed rest in a dark room, but in recent years concussion management has literally come out of the dark. Credit: Shutterstock Public interest in concussion has exploded over the space of a generation, together with a new understanding of how best to help patients recover. Concussion...
by Tracey Peake, North Carolina State University Credit: CC0 Public Domain Researchers from North Carolina State University have discovered that a particular molecular signaling pathway plays an important role in producing osteoarthritis (OA) pain. Using a mouse model of painful osteoarthritis, they show that blocking this signaling pathway eliminates pain and results in a return...
by University of Nottingham Credit: Unsplash/CC0 Public Domain The severity of COVID-19 pneumonia can be difficult to assess in people from different ethnic groups, due to inaccurate readings from a device that measures the level of oxygen in the blood of patients. The findings of the research, published in the European Respiratory Journal, show that pulse...
by Northwestern University Mice treated with novel approach to cell therapy saw dramatic shrinkage in tumors compared to those treated with traditional cell therapy approaches. Credit: Please credit Shana Kelley Lab / Northwestern University Northwestern University scientists have developed a new tool to harness immune cells from tumors to fight cancer rapidly and effectively. Their...
by Delthia Ricks, Medical Xpress Credit: Unsplash/CC0 Public Domain Sleep may be one of the most potent medicines for the brain, scientists are discovering, as they explore the inner labyrinths of the three-pound organ during deep sleep and dream cycles in both health and disease. Among the most active areas of sleep research are those...
by Cold Spring Harbor Laboratory Credit: Pixabay/CC0 Public Domain The process of generating proteins from genes is akin to a factory, where workers follow a set of instructions that, ideally, are effective and clear. But for some people who suffer from cystic fibrosis (CF), one of their genes has a mutation that results in confusing...
by University of Connecticut Credit: Pixabay/CC0 Public Domain Eating more meat, having less of certain bacteria in the gut, and more of certain immune cells in the blood, all link with multiple sclerosis, reports a team of researchers led by UConn Health and Washington University School of Medicine. The work, published in the 27 January...
by Cedars-Sinai Medical Center Credit: Pixabay/CC0 Public Domain The number of people hospitalized for a hypertensive crisis—when blood pressure increases so much it can cause a heart attack, stroke or other sudden cardiovascular event—more than doubled from 2002 to 2014, according to Cedars-Sinai investigators. The increase occurred during a period when some studies reported overall...
