by University of Cambridge Graphical abstract. Credit: Cell Reports (2024). DOI: 10.1016/j.celrep.2024.113700Cambridge scientists may have discovered a new way that fasting helps reduce inflammation, a potentially damaging side-effect of the body’s immune system that underlies a number of chronic diseases. In a paper titled “Arachidonic acid inhibition of the NLRP3 inflammasome is a mechanism to explain...
Peer-Reviewed Publication UNIVERSITY OF CAMBRIDGE Cambridge scientists may have discovered a new way in which fasting helps reduce inflammation – a potentially damaging side-effect of the body’s immune system that underlies a number of chronic diseases. In research published in Cell Reports, the team describes how fasting raises levels of a chemical in the blood...
by Lori Solomon Some patients seen in an inflammatory bowel disease (IBD) clinic screen positive for malnutrition, according to a research letter published online Nov. 20 in Gastro Hep Advances. Aaron C. Viser, from the University of North Carolina at Chapel Hill, and colleagues used data from a multidisciplinary IBD clinic (June 7 to July...
Jan 10 2024Medical University of ViennaAs the cause of chronic inflammatory bowel diseases (IBD) such as Crohn’s disease or ulcerative colitis is not yet known, treatment for sufferers is currently aimed at alleviating the often agonizing symptoms. The discovery by a MedUni Vienna research team that the trigger for IBD could be found on the...
Study suggests stress management could reduce biological riskPeer-Reviewed Publication OHIO STATE UNIVERSITY COLUMBUS, Ohio – Lifestyle and genetics, and a range of other factors within and outside our control, are known to contribute to development of metabolic syndrome, a cluster of conditions that add up to increased risk for serious health problems. A new study...
by Tulane University Transmission electron micrograph of RSV. Credit: CDC/ Dr. Erskine Palmer / Public DomainRespiratory syncytial virus (RSV), a common infection in children and senior adults, can also infect nerve cells and trigger inflammation leading to nerve damage, according to a new Tulane University study. RSV can cause mild symptoms such as coughing, sneezing and...
by Sara Bock, University of California Comparison of HylA and HylB with bacterial and animal Hyl. Credit: Nature Communications (2023). DOI: 10.1038/s41467-023-43833-8In a groundbreaking development in the field of anti-acne therapies, a team of researchers at University of California San Diego School of Medicine has created an acne vaccine that successfully reduces inflammation in a...
by The Mount Sinai Hospital Mice engineered with a patient gene (JAK1 GOF: Neuron) show less lung inflammation, fewer immune cells, and reduced mucous production compared to controls. Credit: Kim et al., Cell. Researchers at the Icahn School of Medicine at Mount Sinai have gained a deeper understanding of the nuanced roles of JAK inhibitors, or...
by Koen Stein, Vrije Universiteit Brussel Panx1-targeting nanobodies interact with the NLRP3 inflammatory cascade in acetaminophen-overdosed mice. a Overview of the NLRP3 signaling cascade in acetaminophen (APAP)-induced hepatotoxicity. Overdosing mice with APAP triggers oxidative metabolization catalyzed by cytochrome (CYP) P450 enzymes in hepatocytes. Associated-NAPQI formation causes necrosis, which triggers a Panx1-mediated inflammatory response in the...
by University of Bonn Immunofluorescence – staining of MAIT cells (green) next to mononuclear phagocytes (red) in kidney sections of mice with experimental glomerulonephritis. Cell nuclei in blue. Credit: Nature Communications (2023). DOI: 10.1038/s41467-023-43269-0Researchers from the University Medical Center Hamburg-Eppendorf and the University Hospital Bonn have demonstrated that certain derivatives of vitamin B2 can alleviate...
