July 26, 2024 by Lori Solomon Hydroxychloroquine appears to be a safe and effective treatment option for anogenital lichen sclerosus that only has mild adverse effects, according to a study published online July 19 in the International Journal of Dermatology. Christeebella O. Akpala, from the Mayo Clinic in Rochester, Minnesota, and colleagues analyzed the demographic...
JULY 12, 2024 by Lori Solomon The U.S. Food and Drug Administration has approved Arcutis Biotherapeutics’ Zoryve (roflumilast) cream, 0.15%, for the treatment of mild-to-moderate atopic dermatitis in adult and pediatric patients (ages 6 years and older). Zoryve is a once-daily, steroid-free cream that the company says will be available at the end of July....
JUNE 25, 2024 by Marcela Quintanilla Dieck, Massachusetts General Hospital Graphical abstract. Credit: Cell Host & Microbe (2024). DOI: 10.1016/j.chom.2024.05.022A new study by investigators from Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham, reveals that particular strains of gut bacteria are linked to inflammatory bowel disease (IBD), a condition that affects...
MAY 15, 2024 by Tokyo University of Science The menthyl esters of valine (MV) and isoleucine (MI) are multi-faceted molecules with enhanced anti-inflammatory and anti-obesity activities. The discovery and development of such molecules can result in newer classes of therapeutic drugs to treat a wide range of metabolic disorders. Credit: Gen-ichiro Arimura from Tokyo University...
Written by Candace Nelson, MS, CN | Reviewed by Katie E. Golden, MD Key takeaways: There are many sources of chronic inflammation in our lifestyle — from stress to diet. And chronic inflammation can put you at risk of long-term health conditions like heart disease and diabetes.Inflammatory foods tend to be processed items that are...
Marilynn LarkinVitamin D levels are unlikely to have an impact on the clinical features of eosinophilic esophagitis (EoE) in adults newly diagnosed with the chronic inflammatory disorder, new research suggests. The substantial increase in EoE incidence and the association of low vitamin D levels with increased risk for allergic sensitization prompted the researchers to assess...
by Salk Institute Human astrocytes (green) extending processes that wrap around the host blood vessel (magenta). Credit: Salk InstituteThe brain is typically depicted as a complex web of neurons sending and receiving messages. But neurons only make up half of the human brain. The other half—roughly 85 billion cells—are non-neuronal cells called glia. The most common...
by British Medical Journal Credit: Pixabay/CC0 Public DomainThe common inflammatory condition sinusitis is linked to a 40% heightened risk of a subsequent diagnosis of rheumatic disease, particularly in the five to 10 years preceding the start of symptoms, according to research published in the open access journal RMD Open. The risks seem to be greatest for...
by Karolinska Institutet Credit: EMBO Molecular Medicine (2024). DOI: 10.1038/s44321-024-00035-zResearchers at Karolinska Institutet have discovered a link between a rare and severe form of psoriatic arthritis and an enzyme that produces oxygen radicals. The study, published in the journal EMBO Molecular Medicine, reveals new ways to slow down or stop the disease progression. Psoriatic arthritis mutilans...
by La Trobe University a, b Deletion of BECLIN1, but not ATG7, by addition of 4-hydroxytamoxifen (4-HT) led to significantly smaller intestinal organoids. a, c There was also a significant reduction in the number of “buds” per organoid formed, indicative of reduced stem cell-containing crypt formation. Credit: Communications Biology (2024). DOI: 10.1038/s42003-024-05890-7La Trobe University researchers have...
