New research, published in the journal Nature Immunology, now shows how a high intake of salt may cause inflammation in multiple sclerosis. salt One recent study reveals how excessive salt consumption may trigger inflammation in people with MS. Multiple sclerosis (MS) is an autoimmune disorder in which the body’s immune system destroys the protective coating...
Category: <span>Inflammation</span>
Post
One type of brain cell might hold key to inflammation after head injury
SAN DIEGO – By eliminating one type of immune cell in the brain, researchers were able to erase any evidence of inflammation following traumatic brain injury, according to a new study from The Ohio State University. “We used a drug to wipe out cells called microglia in mice that had experienced brain injury, and the...
Post
Inflammation can lead to circadian sleep disorders
Novel technology turns inflammation on and off, affecting body clock in mice NORTHWESTERN UNIVERSITY CHICAGO — Inflammation, which is the root cause of autoimmune disorders including arthritis, Type 1 diabetes, irritable bowel syndrome, and Crohn’s disease, has unexpected effects on body clock function and can lead to sleep and shiftwork-type disorders, a new Northwestern Medicine study in...
Post
Scientists uncover why knee joint injury leads to osteoarthritis
Knee joint injuries are typically related to sports, such as football, rugby or ice hockey, but people often do not know that such injuries may lead to joint inflammation and post-traumatic osteoarthritis. In advanced post-traumatic osteoarthritis, joint cartilage breaks down completely, causing severe joint pain, lack of mobility and even social isolation. However, the mechanisms leading to osteoarthritis are not known. Currently, it is not possible...
Post
New study finds that inflammatory proteins in the colon increase incrementally with weight
BOSTON (Oct. 10, 2018)–Studies in mice have demonstrated that obesity-induced inflammation contributes to the risk of colorectal cancer, but evidence in humans has been scarce. A new study shows that two inflammatory proteins in the colon increase in parallel with increasing weight in humans. An incremental rise in these pro-inflammatory proteins (called cytokines) was observed...
Post
Promising novel treatment against Alzheimer disease
New research conducted at the Lady Davis Institute (LDI) at the Jewish General Hospital reveals that a novel drug reverses memory deficits and stops Alzheimer disease pathology (AD) in an animal model. Importantly, this drug has already proven to be non-toxic for humans in a clinical setting and could, therefore, be brought quickly to trials...
Post
People with fibromyalgia have inflammation of the brain
The causes of the difficult-to-treat pain syndrome fibromyalgia are largely unknown. Using PET brain imaging, researchers at Karolinska Institutet and Massachusetts General Hospital have now shown that glial cells – the central nervous system’s immune cells – are activated in the brains of patients with fibromyalgia. The finding has been published in the scientific journal Brain, Behavior, and Immunity and may open the way...
Post
Solving the gut inflammation puzzle
Inflammatory bowel disease (IBD), an umbrella term for a number of gut disorders—including ulcerative colitis and Crohn’s disease—remains a clinical challenge. Current treatments don’t work for all patients, and many stops working over time. But despite their different responses to treatment, all IBD patients share a commonality: intestinal inflammation. A better understanding of what drives...
Post
Improved early diagnosis and treatment for Graves’ orbitopathy
Despite Graves’ disease and Graves’ orbitopathy affecting around 3 million Europeans and costing billions of euros, treatments can only control symptoms. INDIGO identified risk factors, studied microbiota composition and tested probiotics to improve health outcomes. Credit: Perception7, Shutterstock Graves’ disease (GD)—the commonest cause of an overactive thyroid gland—is a chronic autoimmune condition characterized by the...
Post
Malicious brain cell identified
Surprising finding fills gap in understanding astrocytes’ role in brain disease SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE Astrocytes–the star-shaped cells of our brain–are very busy. Their job description includes maintaining the blood-brain barrier, removing excess neurotransmitters, repairing brain tissue and more. IMAGE: THIS IS JEROLD CHUN, M.D., PH.D., PROFESSOR AND SENIOR VICE PRESIDENT OF NEUROSCIENCE...