by Laura Muntean, Texas A&M University Credit: Molecular Metabolism (2023). DOI: 10.1016/j.molmet.2023.101852A team comprised primarily of Texas A&M AgriLife Research scientists has made an important discovery that could lead to a novel treatment for obesity and obesity-associated diseases or conditions. Details of the discovery can be found in the study “Nutrient-sensing growth hormone secretagogue receptor in...
by Impact Journals LLC Resveratrol increases in vitro rhythmic gene mRNA expression of core clock components in human adipose-derived progenitor cells (APCs) from older participants. Credit: Aging (2024). DOI: 10.18632/aging.205292A new research paper was published on the cover of Aging titled, “Effects of resveratrol on in vitro circadian clock gene expression in young and older...
Marilynn Larkin There’s no question that glucagon-like peptide 1 (GLP-1) agonists represent a major advance in the treatment of obesity for patients with or without diabetes. In clinical trials, participants lost 15%-20% of their body weight, depending on the drug. But studies also have shown that once people stop taking these drugs — either by...
by Inka Väth, University Hospital Bonn EPAC1 signaling promotes BAT growth and function in vivo. Credit: Nature Cell Biology (2024). DOI: 10.1038/s41556-023-01311-9Brown fat cells convert energy into heat—a key to eliminating unwanted fat deposits. In addition, they also protect against cardiovascular diseases. Researchers from the University Hospital Bonn (UKB) and the Transdisciplinary Research Area “Life &...
by Jim Oldfield, University of Toronto Graphical abstract. Credit: Cell Reports Medicine (2023). DOI: 10.1016/j.xcrm.2023.101051Researchers at the University of Toronto and its partner hospitals are finding that changes in gut microbiota after bariatric surgery can directly improve metabolism, independent of food intake, weight loss and other metabolic factors. Their ongoing work—including a study published in the...
Peer-Reviewed Publication OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER AN SCHWAB, MD, PHD, IS THE WILLIAM E. HUNT & CHARLOTTE M. CURTIS CHAIR AND A PROFESSOR OF NEUROLOGY AND NEUROSCIENCES AT THE Ohio State College of Medicine. SCHWAB IS ALSO MEDICAL DIRECTOR OF THE Belford Center for Spinal Cord Injury AND A SCHOLAR OF THE CHRONIC...
Peer-Reviewed Publication UNIVERSITY OF COLOGNE PICTURES SHOW SMALL INTESTINAL VILLI FROM WILD TYPE (TOP) AND ENTEROCYTE-SPECIFIC DARS2 KNOCKOUT MICE (BOTTOM) STAINED FOR PLIN2 (YELLOW), TGN38 (RED), E-CADHERIN (GREEN) AND DNA (DAPI, BLUE). CREDIT: CHRYSANTHI MOSCHANDREA The maintenance of a balanced lipid homeostasis is critical for our health. While consumption of excessive amounts of fatty foods...
by Andy Miller, KFF Health News Credit: Pixabay/CC0 Public Domain After years of debilitating bouts of fatigue, Beth VanOrden finally thought she had an answer to her problems in 2016 when she was diagnosed with Hashimoto’s disease, an autoimmune disorder. For her and millions of other Americans, that’s the most common cause of hypothyroidism, a...
by Nahia Barberia, Institute for Research in Biomedicine (IRB Barcelona) On the right, cells in the pancreas undergoing reprogramming; on the left, regular pancreas tissue. Credit: IRB BarcelonaVitamin B12 is a well-known micronutrient that has long been acknowledged for its essential role in maintaining nerve function, supporting red blood cell production, and facilitating DNA synthesis,...
by Physicians Committee for Responsible Medicine Graphical Abstract. Credit: Complementary Therapies in Medicine (2023). DOI: 10.1016/j.ctim.2023.103002 A low-fat vegan diet that includes soy fosters changes in the gut microbiome that decrease postmenopausal vasomotor symptoms, or hot flashes, overall by 95%, according to a new study by the Physicians Committee for Responsible Medicine. A vegan diet...
