by King’s College London Credit: CC0 Public Domain Eating in a ten-hour window is associated with higher energy and mood and lower hunger levels, new results from the largest UK community science study of its kind shows. Results from the trial are presented today by researchers from King’s College London at the European Nutrition Conference in...
by Duke-NUS Medical School Credit: Cell Metabolism (2023). DOI: 10.1016/j.cmet.2023.08.001 Scientists from Duke-NUS Medical School, in collaboration with counterparts from Columbia University, have developed a new framework to measure metabolic health. The concept of “metabolic elasticity” paints a more comprehensive picture of how the body reacts to changes in the availability of food and how efficiently...
by Karolinska Institutet Credit: CC0 Public Domain An early phase in the process of developing Alzheimer’s disease is a metabolic increase in a part of the brain called the hippocampus, report researchers from Karolinska Institutet in a study published in Molecular Psychiatry. The discovery opens up for new potential methods of early intervention. Alzheimer’s disease is...
by Isy Godfrey, Institute of Cancer Research The complex tumour immune microenvironment in patient samples of muscle-invasive bladder cancer, captured using develop a new multiplex immunofluorescence panel. Credit: Integrative Pathology Unit at The ICR and The Royal Marsden NHS Foundation TrustFor generations, the medical community has used the “standard human”—a 70-kilogram male—to guide education, research and...
by Medical Research Council Credit: iScience (2023). DOI: 10.1016/j.isci.2023.106590New research from QIMR Berghofer has found that the hormone testosterone may play an important role in the development of endometrial cancer. The discovery raises exciting new possibilities for screening, preventing and fighting this increasingly prevalent disease. Endometrial cancer is the fourth most common cancer in Australian...
by University of Montreal Credit: Pixabay/CC0 Public DomainCanadian scientists have found a new link between two major metabolic diseases: diabetes and steatotic liver disease, commonly known as fatty liver disease. Published in Diabetes, research into the two diseases by Université de Montréal medical professor Jennifer Estall and her team at the Montreal Clinical Research Institute (IRCM)...
Courtney Southwick October 17, 2023 A process your body uses to stay warm in cool weather could one day lead to new therapies for obesity. Scientists have, for the first time, mapped the precise nerve pathways that activate brown fat, or brown adipose tissue (BAT), a specialized fat that generates heat. Low temperatures kick brown fat into...
by Buck Institute for Research on Aging Credit: CC0 Public DomainPeople overeat and become overweight for a variety of reasons. The fact that flavorful high-calorie food is often available nearly everywhere at any time doesn’t help. Buck researchers have determined for the first time why certain chemicals in cooked or processed foods, called advanced glycation...
Miriam E. Tucker October 06, 2023 HAMBURG, Germany — The “twincretin” tirzepatide (Mounjaro) kept on producing “highly significant weight loss” when the drug was continued in a 1-year follow-up trial, and those who discontinued the drug regained some weight but not all. In Eli Lilly’s SURMOUNT-4 trial of 783 adults with obesity or overweight but not diabetes...
by Ingrid Fadelli , Medical Xpress The medial preoptic area mediates depressive-like behaviors associated with ovarian hormone fluctuations Electrophysiological recording from MPOA GABAergic neurons (Vgat+) demonstrated that these neurons reduced their spiking activity in HW-treated mice compared to non-HW controls (NHW). Credit to Can Tao.Fluctuations in the hormones secreted by women’s ovaries, namely estrogen and...
