Peer-Reviewed Publication UNIVERSITY OF COLOGNE PICTURES SHOW SMALL INTESTINAL VILLI FROM WILD TYPE (TOP) AND ENTEROCYTE-SPECIFIC DARS2 KNOCKOUT MICE (BOTTOM) STAINED FOR PLIN2 (YELLOW), TGN38 (RED), E-CADHERIN (GREEN) AND DNA (DAPI, BLUE). CREDIT: CHRYSANTHI MOSCHANDREA The maintenance of a balanced lipid homeostasis is critical for our health. While consumption of excessive amounts of fatty foods...
Category: <span>Metabolic</span>
Many autoimmune disease patients struggle with diagnosis, costs, inattentive care
by Andy Miller, KFF Health News Credit: Pixabay/CC0 Public Domain After years of debilitating bouts of fatigue, Beth VanOrden finally thought she had an answer to her problems in 2016 when she was diagnosed with Hashimoto’s disease, an autoimmune disorder. For her and millions of other Americans, that’s the most common cause of hypothyroidism, a...
Study finds vitamin B12 is a key player in cellular reprogramming and tissue regeneration
by Nahia Barberia, Institute for Research in Biomedicine (IRB Barcelona) On the right, cells in the pancreas undergoing reprogramming; on the left, regular pancreas tissue. Credit: IRB BarcelonaVitamin B12 is a well-known micronutrient that has long been acknowledged for its essential role in maintaining nerve function, supporting red blood cell production, and facilitating DNA synthesis,...
Vegan diet fosters changes in gut microbiome that reduce hot flashes by 95%, finds new study
by Physicians Committee for Responsible Medicine Graphical Abstract. Credit: Complementary Therapies in Medicine (2023). DOI: 10.1016/j.ctim.2023.103002 A low-fat vegan diet that includes soy fosters changes in the gut microbiome that decrease postmenopausal vasomotor symptoms, or hot flashes, overall by 95%, according to a new study by the Physicians Committee for Responsible Medicine. A vegan diet...
New research finds that 14-hour fasting improves hunger, mood and sleep
by King’s College London Credit: CC0 Public Domain Eating in a ten-hour window is associated with higher energy and mood and lower hunger levels, new results from the largest UK community science study of its kind shows. Results from the trial are presented today by researchers from King’s College London at the European Nutrition Conference in...
‘Metabolic elasticity’: New screening strategy, possible means to curb metabolic decline in aging and obesity
by Duke-NUS Medical School Credit: Cell Metabolism (2023). DOI: 10.1016/j.cmet.2023.08.001 Scientists from Duke-NUS Medical School, in collaboration with counterparts from Columbia University, have developed a new framework to measure metabolic health. The concept of “metabolic elasticity” paints a more comprehensive picture of how the body reacts to changes in the availability of food and how efficiently...
High metabolism is an early sign of Alzheimer’s disease, finds study
by Karolinska Institutet Credit: CC0 Public Domain An early phase in the process of developing Alzheimer’s disease is a metabolic increase in a part of the brain called the hippocampus, report researchers from Karolinska Institutet in a study published in Molecular Psychiatry. The discovery opens up for new potential methods of early intervention. Alzheimer’s disease is...
We can’t defeat cancer without acknowledging the differences between men and women, say scientists
by Isy Godfrey, Institute of Cancer Research The complex tumour immune microenvironment in patient samples of muscle-invasive bladder cancer, captured using develop a new multiplex immunofluorescence panel. Credit: Integrative Pathology Unit at The ICR and The Royal Marsden NHS Foundation TrustFor generations, the medical community has used the “standard human”—a 70-kilogram male—to guide education, research and...
Common hormone could hold key to treating endometrial cancer
by Medical Research Council Credit: iScience (2023). DOI: 10.1016/j.isci.2023.106590New research from QIMR Berghofer has found that the hormone testosterone may play an important role in the development of endometrial cancer. The discovery raises exciting new possibilities for screening, preventing and fighting this increasingly prevalent disease. Endometrial cancer is the fourth most common cancer in Australian...
New link found between diabetes and steatotic liver disease
by University of Montreal Credit: Pixabay/CC0 Public DomainCanadian scientists have found a new link between two major metabolic diseases: diabetes and steatotic liver disease, commonly known as fatty liver disease. Published in Diabetes, research into the two diseases by Université de Montréal medical professor Jennifer Estall and her team at the Montreal Clinical Research Institute (IRCM)...