Seeking strategic partners for continued clinical development of PBCLN-010 with PBCLN-014, a lead investigational therapy comprising human milk sugars and gut bacteria found in nursing infants Business Announcement PROLACTA BIOSCIENCE DUARTE, Calif., Nov. 10, 2023 – In a breakthrough for human milk science, researchers at City of Hope, Los Angeles, have dosed the first patient...
Category: <span>Stem Cell Therapy</span>
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New study calls into question the superiority of stem cell therapy for treating knee pain
by Brian Katzowitz, Emory University Credit: Pixabay/CC0 Public Domain Characterized by extensive damage to joints and debilitating pain, osteoarthritis (OA) impacts millions of people worldwide and has long posed a substantial clinical and economic burden. In spite of advances in diagnosis, medications, and short-term pain management solutions, the elusive goal of a disease-modifying OA drug has...
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Study reveals that dental pulp stem cells and their products could help regenerate peripheral nerves and more
by World Journal of Stem Cells Advantages of dental pulp stem cells as alternative stem cells for nerve regeneration. The figure was created with BioRender.com. DPSCs: Dental pulp stem cells. Credit: World Journal of Stem Cells (2023). DOI: 10.4252/wjsc.v15.i10.960 Peripheral nerve injury (PNI) seriously affects people’s quality of life. Stem cell therapy is considered a promising new...
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HKUST researchers find how stem cell niche guides differentiation into functional cells, significant step towards stem cell therapies
Peer-Reviewed PublicationHONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY IMAGE: A MODEL OF HOW STEM CELL NICHE USES THE PROTEIN CHANNELS “GAP JUNCTIONS” TO TRANSPORT ITS CAMP INTO STEM CELL PROGENY IN CONTROLLING THEIR DIFFERENTIATION INTO FUNCTIONAL CELLS. CREDIT: HKUST Researchers at the Hong Kong University of Science and Technology (HKUST) have found how stem cells’...
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Genetically modified neural stem cells show promising therapeutic potential for spinal cord injury
by City University of Hong Kong The transplanted SOX9-suppressed neural stem cells (bottom) at injured site generated robust axons extending into the host spinal cord after 3 months post-graft. Credit: Advanced Science (2023). DOI: 10.1002/advs.202205804 A research team co-led by City University of Hong Kong (CityU) and The University of Hong Kong (HKU) has recently made a significant...
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University of Minnesota-led study demonstrates safety of microbiota transplant therapy in stem cell transplant and leukemia patients
UNIVERSITY OF MINNESOTA MEDICAL SCHOOL MINNEAPOLIS/ST. PAUL (07/06/2023) — Published in the Journal of Clinical Oncology, University of Minnesota Medical School researchers led a study that demonstrated the safety of using microbiota transplant therapy (MTT) in patients with acute myeloid leukemia (AML) — a type of blood cancer — and recipients of hematopoietic cell transplantation (HCT). Current...
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Researchers discover secret of stem cells protecting the gastric mucosa
by Nara Institute of Science and Technology The gastric corpus, which is a major component of the glandular stomach, is composed of parietal, chief, pit, and neck cells. Each of these specialized epithelial cells play an important role in digestion, and they are continuously replenished by new ones which are formed via the differentiation of...
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Baldness breakthrough? New RNA treatment may stimulate hair growth
Scientists may have made a breakthrough in the treatment of baldness by using a tiny RNA particle to stimulate hair growth. The study revealed that hair follicles become stiff with age, making it harder for hair to grow. However, by softening the stem cells through the production of a specific RNA called miR-205, researchers at Northwestern University...
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Scientists develop universal donor stem cell therapy to treat degenerative brain diseases in a preclinical study
by Zen Logsdon, City of Hope National Medical Center City of Hope’s Yanhong Shi, Ph.D., and her colleagues engineered healthy human skin cells containing the functional aspartoacylase (ASPA) gene into induced pluripotent stem cells (iPSCs) and then differentiated the iPSCs into oligodendroglial progenitor cells, the precursor cells that produce myelin, an insulating sheath that wraps around...
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Breakthrough research could bring stem cell therapy to the masses
by Justin Jackson , Phys.org Allogeneic HIP islets achieve long-term survival. a, Immunofluorescence pictures of dissociated and reaggregated wtallo and HIPallo islets from rhesus monkeys (representative images). b, In vitro insulin secretion of wtallo and HIPallo islets (mean ± s.d., triplicates). c, The composition of wtallo and HIPallo islets of α, β, δ and other cells (mean, triplicates). d, Flow cytometry...